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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK2
All Species:
16.97
Human Site:
S456
Identified Species:
31.11
UniProt:
Q7KZI7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7KZI7
NP_001034558.2
788
87911
S456
S
T
A
K
V
P
A
S
P
L
P
G
L
E
R
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
S463
D
V
A
R
K
L
G
S
T
T
V
G
S
K
S
Rhesus Macaque
Macaca mulatta
XP_001115591
788
87964
S456
S
T
A
K
V
P
A
S
P
L
P
G
L
E
R
Dog
Lupus familis
XP_540890
798
88683
S475
S
T
A
K
V
P
A
S
P
L
P
G
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q05512
776
86287
S453
S
T
A
K
V
P
A
S
P
L
P
G
L
D
R
Rat
Rattus norvegicus
O08679
722
80853
P403
Q
R
S
V
S
A
N
P
K
Q
R
R
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
S462
D
V
S
R
K
L
S
S
T
T
V
G
S
K
G
Chicken
Gallus gallus
Q9IA88
798
88848
I457
E
K
E
L
E
D
E
I
K
A
Y
D
H
P
I
Frog
Xenopus laevis
NP_001080425
785
87931
P460
T
V
R
V
P
P
S
P
L
S
G
L
D
R
K
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P551
T
Q
Q
L
L
K
R
P
R
G
Q
S
P
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
P573
H
Q
Q
S
S
A
A
P
S
S
G
S
S
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
K192
A
P
E
V
I
S
G
K
L
Y
A
G
P
E
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L314
K
V
D
L
P
E
Y
L
L
P
P
D
L
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
99.7
95.1
N.A.
96.6
89.9
N.A.
68.4
30.3
84.3
27.5
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
80.4
99.7
96.2
N.A.
97.7
90.9
N.A.
80.5
48.7
91.7
42.7
N.A.
N.A.
N.A.
49.9
N.A.
P-Site Identity:
100
20
100
100
N.A.
93.3
0
N.A.
13.3
0
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
6.6
N.A.
40
0
26.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.5
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
39
0
0
16
39
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
0
8
0
0
0
0
0
16
8
8
8
% D
% Glu:
8
0
16
0
8
8
8
0
0
0
0
0
0
31
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
0
8
16
54
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
8
8
0
31
16
8
0
8
16
0
0
0
0
24
8
% K
% Leu:
0
0
0
24
8
16
0
8
24
31
0
8
39
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
16
39
0
31
31
8
39
0
16
8
8
% P
% Gln:
8
16
16
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
8
8
16
0
0
8
0
8
0
8
8
0
8
31
% R
% Ser:
31
0
16
8
16
8
16
47
8
16
0
16
31
16
16
% S
% Thr:
16
31
0
0
0
0
0
0
16
16
0
0
0
0
0
% T
% Val:
0
31
0
24
31
0
0
0
0
0
16
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _